The goal of this two-year training program is to provide the fellow with specialized skills in clinical pharmacokinetic/pharmacodynamic/pharmacogenomic study design, methodology, and data analysis and presentation. The fellow will collaborate in ongoing clinical research investigations including studies of drug metabolism/transport, drug-drug interactions, drug-gene interactions, and dose-escalation/dose-safety/tolerability in addition to developing and initiating individual research projects.
The program will provide ample opportunity for the fellow to gain expertise in pharmacokinetic data analysis (using software programs such as WinNonlin), statistical analysis, study protocol design, scientific writing, and grantsmanship. Opportunity to gain exposure in drug assay development and validation procedures will be provided, as will opportunities for advanced coursework in clinical research/drug development, clinical pharmacology, pharmacokinetics, biostatistics, and genetics.
The fellow will attend scientific meetings (at least one per year) where he/she will present preliminary scientific data in abstract or poster form; manuscript preparation and publication will follow. The fellow will also have the opportunity to participate in clinical activities in the National Institute of Allergy and Infectious Diseases (NIAID) Outpatient HIV Clinic.
Applicants are strongly encouraged to set up interviews at ASHP Midyear via Personal Placement Service (PPS). Formal applications are due by January 1. Applicants will be required to submit a Cover Letter/Letter of Interest, 3 professional letters of reference, a CV, and an unofficial transcript to be emailed directly to:
The applicant should possess a Pharm.D. degree and a strong interest and basic skills in clinical pharmacokinetics and clinical research.
Preference will be given to candidates that have completed a prior Pharmacy Practice and/or specialty residency (or Post-BS Pharm.D).
About National Institutes of Health
The Clinical Center at the National Institutes of Health (NIH) in Bethesda, Maryland, is the nation's largest hospital devoted entirely to clinical research. It is a national resource that makes it possible to rapidly translate scientific observations and laboratory discoveries into new approaches for diagnosing, treating, and preventing disease. Approximately 1,500 studies are in progress at the NIH Clinical Center. Most are Phase I and Phase II clinical trials. The Clinical Center is part of the NIH’s intramural science research program and the NIH is the medical research agency of the U.S Government. It is part of the U.S. Department of Health and Human Services.
The Clinical Center promotes translational research -- that is, the transference of scientific laboratory research into applications that benefit patient health and medical care. The "bench-to-bedside" approach adopted in 1953, locates patient care units in close proximity to cutting-edge laboratories doing related research. This facilitates interaction and collaboration among clinicians and researchers. Most important, patients and families in the Clinical Center benefit from the cutting-edge technologies and resear...ch and the compassionate care that are the signature of NIH.
The Mark O. Hatfield Clinical Research Center was opened in 2005. The facility houses inpatient units, day hospitals and research labs and connects to the original Warren Grant Magnuson Clinical Center. Together, the Magnuson and Hatfield buildings form the NIH Clinical Center. They serve the dual role of providing humane and healing patient care and the environment clinical researchers need to advance clinical science. It was named in honor of Senator Mark O. Hatfield of Oregon, who supported medical research throughout his congressional career. The 870,000 square foot Hatfield building has 242 inpatient beds and 90 day-hospital stations.