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Program Purpose Statement

The purpose of the second-year pharmacy residency program in Thrombosis and Hemostasis Management is to provide advanced training and clinical expertise to licensed pharmacists with a PGY1 residency in the specialized field of anticoagulation and hemostasis. This program equips residents with the skills and knowledge needed for excellence in various clinical roles, including inpatient and outpatient anticoagulation management, anticoagulation and hemostasis consultation services, and active participation in anticoagulation management programs. Upon successful completion of the PGY2 pharmacy residency, residents will be expected to demonstrate the competencies required to contribute effectively to patient care, optimize anticoagulation therapy, and advance the field of thrombosis and hemostasis management.

Residency Goals

The PGY2 Thrombosis and Hemostasis pharmacy residency program builds on Doctor of Pharmacy (PharmD) education and PGY1 pharmacy residency programs to contribute to the development of clinical pharmacists with a specialty in thrombosis and hemostasis management. Residents who successfully complete the PGY2 thrombosis and hemostasis pharmacy residency are prepared for advanced patient care, academic, or other specialized positions.

1. Clinical Expertise: Develop advanced clinical knowledge and expertise in thrombosis and hemostasis management.
2. Patient Care: Provide direct patient care services related to anticoagulation and treatment of thrombosis and bleeding, optimizing therapy, and ensuring patient safety.
3. Interdisciplinary Collaboration: Collaborate effectively with healthcare professionals to enhance patient outcomes and contribute to a comprehensive approach to patient care.
4. Medication Management: Optimize medication therapy by actively participating in anticoagulation dosing and monitoring, including adjusting doses as needed.
5. Education and Training: Engage in educating healthcare professionals, patients, and caregivers concerning thrombosis and hemostasis management.
6. Research and Scholarly Activity: Contribute to the advancement of knowledge in the field through research and scholarly activities, including presentations and publications.

Training Site

The Hospital of the University of Pennsylvania (HUP) is a robust 988-bed hospital with a wide range of specialties actively involved in thrombosis and hemostasis management, including cardiovascular medicine, interventional cardiology, hematology, interventional vascular radiology, pulmonary embolism response team, and the vascular neurology program. Within the hospital, the Anticoagulation Inpatient Management (AIM) team plays a crucial role in collaborating with other healthcare providers and serves as an invaluable source on anticoagulants and their reversals.

Additionally, the outpatient Anticoagulation Management Center (AMC), which oversees the ambulatory anticoagulation needs of over 1400 patients yearly, operates as a multidisciplinary unit. This team includes nurse practitioners, pharmacists, clinicians, practicing nurses, and administrative staff working together to provide comprehensive anticoagulation care. In the outpatient clinic, patients receive personalized care through on-site point-of-care testing and telephone-based management for remote INR monitoring. The AMC coordinates with other ambulatory physicians to deliver safe and effective care for patients who require interruptions of therapy, changes to the duration of therapy, or transitions between anticoagulants.

Pediatric hemostasis & thrombosis is also offered as an elective through the Children’s Hospital of Philadelphia (CHOP), located adjacent to HUP. Participation requires additional screening and credentialing and may involve unreimbursed costs due to institutional requirements.

The HUP Pharmacy Department is one of four recipients of the Anticoagulation Forum TRAIN Grant for PGY2 Thrombosis and Hemostasis Residents in 2024-2025 and 2025-2026.

Learning Experiences

Required Rotations

• Orientation
• Anticoagulation Inpatient Management (AIM)
• Anticoagulation Management Center (AMC)
• Benign Hematology
• Cardiac Intensive Care Unit
• Coagulation Laboratory
• Heart and Vascular Intensive Care Unit
• Neurocritical Care Intensive Care Unit

Elective Rotations

• Benign Hematology
• Pediatric Hemostasis & Thrombosis (CHOP)

Elective Rotations

• Repeat of any required rotation
• General Cardiology

Longitudinal Activities

• Anticoagulation Subcommittee
• Clinical On-Call
• Grand Rounds (1-hour ACPE accredited departmental continuing education presentation)
• Hemophilia Clinic (Ambulatory)
• Medication Use Evaluation
• Pharmacogenomics and Clinic
• Staffing & Pharmacy Operations (CICU/AIM)
• Therapeutics Conference
• THM Clinical Research
• Topic discussions with other AC Forum Train Grant sites
• Ventricular Assisted Device clinic (ambulatory)

Additional Activities

• Completion of ASHP Anticoagulation Certificate Program
• Precept pharmacy students, PGY1 residents, and other healthcare providers
• Represent the AIM and AMC services at pharmacy department meetings
• Attendance at conferences such as the AC Forum, THSNA
• Educational hematology seminars

Residency Program Director

Pardis Niami, PharmD, CACP
Clinical Pharmacy Specialist, Anticoagulation Inpatient Management
Hospital of the University of Pennsylvania
Department of Pharmacy
3400 Spruce Street | Philadelphia, PA 19104
Email: Pardis.Niami@pennmedicine.upenn.edu

Program Website: PGY2 Pharmacy Thrombosis and Hemostasis Management Residency